Synthesis of 2-Pyridone from 2-Thiopyridines via Nucleophilic Aromatic Substitution Reaction

2-Thiopyridine has been used for the synthesis of 2-pyridones. Aromatic nucleophilic substitution reaction has been utilized for the transformation of 2-pyridine into 2-pyridones. Reusability of the released dithiol into generation of 2-thiopyridine explores reactivity of thiol as a template in synthesis of pyridine core. The present method explores making 2-pyridone derivatives utilizing 2-thiopyridines whereas thiol act as a template for pyridine synthesis.