Abstract
In today’s environment, infertility is a worldwide health concern. It is a social stigma in countries like India. The etiology behind it is multifactorial. Disorders related to thyroid gland and hyper prolactinemia have substantial contribution towards the causation of female infertility. The current research was conducted to evaluate the prolactin and thyroid profiles of infertile females in the reproductive age group, as well as any association between the two, in light of the aforementioned results. One hundred infertile women had their serum levels of prolactin, thyroid stimulating hormones (TSH), free tri-iodothyronine (FT3), and free thyroxine (FT4) evaluated. The findings were compared to those of one hundred age-matched women. Among the infertile individuals, correlations between blood prolactin and serum TSH, FT3, and FT4 were also found. When compared to controls, infertile patients have a large rise in TSH and prolactin and a considerable drop in FT4. Serum prolactin has a substantial negative connection with both FT3 and FT4, and a significant positive correlation with TSH in infertile cases. Hyperprolactinemia and abnormal thyroid profiles have a major impact on a childbearing woman’s fertility.
Keywords: Infertility, Prolactin, Tri-Iodothyronine, Thyroxine.