ABSTRACT
The human immunodeficiency virus is the cause of AIDS, which attacks the body’s immune system. This retrovirus transmits through blood, semen, and breast milk that infects immune cells and destroying their functions. In 1995, Food and Drug Administration approved highly active antiretroviral therapy treatment, which has accelerated the abrupt drop of between 60% and 80% in rates of AIDS-associated deaths in several countries globally. After two decades, for the first time in 2017, more than half of the world’s populations living with HIV are receiving antiretroviral therapy. The antiretroviral therapy is most common and suitable process. However, it creates pill burden, toxicity. Therefore, recent developments like nanotechnology shock and kill process, mRNA technology, Gene editing helps to reduce pill burden. The paper throws light on the mean infection rate, recovery rate, and active cases. For that, world’s death rate is under control. Living with HIV rates are increasing. Mortality rate is decreasing. The researcher tries to collate the latest advancements in Management and Treatment of Epidemiology immunodeficiency complexities, in this case HIV disease. The major thrust is on the effective management & treatment.
Key words: Epidemiology Management, immunodeficiency, antiretroviral therapy, Nanotechnology, disease control.