journals

Abstract Ribosomes are large ribonucleoprotein complexes that have been proved to be ideal biological sample for the development of the cryo-Electron Microscopy (cryo-EM) field. On the other hand, advancement in cryo-EM technologies have helped in elucidating detailed structure-function aspects of various kinds of ribosomes, belonging to prokaryotic, organellar, and complex eukaryotic systems. In a relatively […]

Abstract The Erythrocyte Binding Ligand (EBL) is an important protein of Plasmodium sp. required by the parasite for successful invasion into the red blood cells causing malaria. EBL is a potential anti-malarial drug target. Despite its importance only a portion of its structure i.e., Duffy Binding Domain (DBD), is solved. Thus, the remaining regions necessitate

Abstract Mother-child bonding is not confined to human beings, rather all living animals show baby love. It is quite interesting to intervene in the mechanisms or causative factors of this affection and its consequences. In this article, we attempt to delineate that the chemical factors could be responsible for the affection or aggressiveness which ultimately

Abstract Introduction: Birth defect refers to any abnormality of physical structure or form or function of prenatal origin, whether genetic or not, which is present at birth. Congenital birth defect is one of the causes of perinatal morbidity and mortality especially in developed countries. Studies of congenital birth defects are useful to establish baseline data,

Abstract Increasing peer-pressure for publishing research articles accounts for the several instances of misconducts in the form of fabrication, falsification, plagiarism, salami slicing and authorship related issues. Advancement in technology has not only enabled the process of speedy publications but also the detection of unethical practices. Instances of paper retraction and suspension of authors is

Abstract Endophytes are unknown symbionts that live in plant tissues without indicating their presence. The association of endophytes with plants is well established. They not only help in water and mineral uptake but also play an important role in metabolic activities of certain plants. Endophytes play an imperative role to maintain the health of plants,

Abstract 2-Thiopyridine has been used for the synthesis of 2-pyridones. Aromatic nucleophilic substitution reaction has been utilized for the transformation of 2-pyridine into 2-pyridones. Reusability of the released dithiol into generation of 2-thiopyridine explores reactivity of thiol as a template in synthesis of pyridine core. The present method explores making 2-pyridone derivatives utilizing 2-thiopyridines whereas

Abstract Aims: The aim of the study was to assess the use of contraceptive methods among women seeking safe abortion services in a family planning center, Kathmandu. Methods: It was a descriptive cross sectional study undertaken among 119 women seeking safe abortion services from August 18 to September 2018 at Marie Stopes Center, Gongabu, Kathmandu.

Abstract Sphagneticola trilobata (L.) Pruskiis a perennial herb, it belongs to the tribe Heliantheae of family Asteraceae.  S. trilobata has traditionally been used to treat infections, indigestion and hepatitis; it shows antibacterial, antifungal activity (1). To standardize and differentiate the species anatomical features such as anatomy of nodes, petioles and leaves and dermatological parameters were